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Having memory that will run reliably at a (250x2)Mhz memory clock is an excellent solution for the overclocker wishing to get the most from their system. When it comes to the average enthusiast that may not overclock on a regular basis the relaxed timings have a detrimental effect to system performance. This can be overcome by manually adjusting the memory timings though given the wide abundance of excellent DDR400 and 433 modules the XMS4000 might not be the best choice.
The Corsair XMS4000 TwinX memory is clearly overclocking memory for the avid overclocker.
Real paired memory
Ability to run overclocked at 1:1
Cooler Running memory
Heat spreaders that work
Higher SPD Programmed Latency
No economical benefit to DDR500, yet